PROBLEM TO BE SOLVED: To provide a method of easily and accurately analyzing the dynamic state of intradermal moisture by means of the Raman spectrometry.SOLUTION: The method of measuring the intradermal moisture quantity is a method of measuring the dermal moisture quantity by measuring Raman spectra of the skin infiltrated in heavy water and computing the heavy water quantity based on the ratio of the signal intensity of heavy water to the signal intensity of protein in the obtained Raman spectra.COPYRIGHT: (C)2010,JPO&INPIT【課題】ラマン分光測定法により、皮膚内部の水の動態を簡便にかつ正確に解析する方法を提供する。【解決手段】皮膚内部の水分量の測定方法であって、重水を浸透させた皮膚のラマンスペクトルを測定し、得られたラマンスペクトル中の重水の信号強度と蛋白質の信号強度の比に基づき重水分量を算出することにより測定する皮膚水分量の測定方法。【選択図】なし