A syringe with needle 2 according to the present invention has: an outer cylinder 10 including an outer cylinder body part 21 and a needle fixing part 22 provided at a distal end part of the outer cylinder body part； an injection needle 6 having a puncturing needle tip 61 at a distal end and fixed to the needle fixing part 22； and a gasket 4 housed in the outer cylinder. The injection needle 6 is such a tapered part holding injection needle that a puncturing time piercing part 65 having a needle tip has an outer diameter of 0.42 mm or less and has a thickness of 0.1 mm or less, or the injection needle 6 is such a small diameter thin injection needle as to have a thickness of 0.04 mm or less. A lubricant is not applied to an inner surface of the outer cylinder. The gasket 4 includes a gasket body 41 and a soft coating 42 provided on a portion that comes into contact with the inner surface of the outer cylinder, the soft coating 42 having an adhesive property to the gasket body and a liquid-tight sliding property with respect to the inner surface of the outer cylinder.
