FERRARA, NAPOLEONE,HILLAN, KENNETH J.,LE COUTER, JENNIFER
申请号：
CA2486270
公开号：
CA2486270C
申请日:
2003.06.05
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention provides pharmaceutical compositions and methods forliverproliferation and protection. Specifically useful are VEGFR modulating agentscapable ofpromoting liver growth. For example, VEGFR modulating agents include Flt-1agonistsselected from the group consisting of P1GF, VEGF-B, and a Flt-1 selectivevariant (Flt-sel)that selectively binds to Flt-1. Disclosed compositions and methods may beuseful forpromoting proliferation or treating pathological conditions in other organs ofsignificantbiological functions.
