DIFLUORLACTAM COMPOUNDS AS EP4 RECEPTOR SELECTIVE AGONISTS TO USE IN TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS

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专利权人:

Cayman Chemical Company; Incorporated

发明人:

BARRETT, Stephen, Douglas,CISKE, Fred, Lawrence,COLOMBO, Joseph, Michael,ENDRES, Gregory, William,GERMAIN, Bradlee, David,KORNILOV, Andriy,KRAMER, James, Bernard,UZIEBLO, Adam,MAXEY, Kirk, M.

申请号：

DK13745744

公开号：

DK2875022T3

申请日:

2013.07.19

申请国别(地区):

DK

年份:

2017

代理人:

摘要：

Disclosed herein are compounds of formula (I) and therapeutic methods of treatment with compounds of formula (I), wherein L 1 , L 2 , L 4 , R 1 , R 4 , R 5 , R 6 , and s are as defined in the specification. Compounds of formula (I) are EP4 agonists useful in the treatment of glaucoma, neuropathic pain, and related disorders.

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