Provided is a compound that has an Inhibitory activity of mpges-1 and which is useful for the Prevention or treatment of Pain, Fever, rheumatism, Osteoarthritis, Alzheimers disease, multiple sclerosis, atherosclerosis, glaucoma, ocular hypertension, retinal disease isqu\u00e9 Mica, Systemic Scleroderma and cancers, including colorectal cancer.Claim 1: a compound represented by the formula [1] or one of its pharmaceutically acceptable salts, wherein X is n or CH Ring Cy is the formula or formula [2] [3] {where r\u00b9 is (1) (2) c\u2081\u208b\u2086 Halogen, alkyl, cyano, or (3) 4) haloalquilo c\u2081\u208b\u2084 R\u00b2 is (1) (2) Halogen, Hydroxy, carboxy, (3) (4) (5) c\u2081\u208b\u2086 alkyl, alkoxy c\u2081\u208b\u2086, haloalcoxi c\u2081\u208b\u2084 (6), (7) haloalquilo c\u2081\u208b\u2084,C\u2081\u208b\u2086 alkyl carbonyl (8) - (9) - C (o) nr\u1d43\u00b9r\u1d43\u00b2 (r\u1d43\u00b9 and r\u1d43\u00b2 are each, independently, hydrogen or alkyl c\u2081\u208b\u2086) or (10) - (c\u2099h\u2082\u2099) - r\u1d47 (n is 1, 2, 3, or 4 - (c\u2099h\u2082\u2099) - can be Chain linear or branched, and r\u1d47 is (a) (b), carboxy, Hydroxy, alkoxy c\u2081 (c) \u208b\u2086, c\u2081\u208b\u2086 carbonyloxy alkyl - (d), (e) - C (o) nr\u1d47\u00b9r\u1d47\u00b2 (r\u1d47\u00b9 and r\u1d47\u00b2 are each, independently, hydrogen or alkyl, c\u2081\u208b\u2086)(f) - (or nr\u1d47\u00b3r\u1d47\u2074 (OC) and r\u1d47\u00b3 r\u1d47\u2074 are each, independently, hydrogen or alkyl c\u2081\u208b\u2086), (g) - nr\u1d47\u2075c (OR) nr\u1d47\u2076r\u1d47\u2077 (r\u1d47\u2075, r\u1d47\u2076 and r\u1d47\u2077 are each, independently, hydrogen or alkyl c\u2081\u208b\u2086), (H) and (r\u1d47\u2078 nr\u1d47\u2078r\u1d47\u2079 r\u1d47\u2079 are each, Independently Hydrogen, alkyl or c\u2081\u208b\u2086 haloalquilo c\u2081\u208b\u2084), (R) - nr\u1d47\u00b9\u2070s (OR) \u2082r\u1d47\u00b9\u00b9 (r\u1d47\u00b9\u2070 and r\u1d47\u00b9\u00b9 are each, independently, hydrogenC\u2081\u208b\u2086 alkyl or cy
