Northwestern University;The Trustees of Columbia University in the City of New York
发明人:
申请号:
EP14762602.2
公开号:
EP2968322B1
申请日:
2014.03.17
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The invention provides novel MAP kinase inhibitors of formula (I) and compositions comprising the same. In some embodiments, the MAP kinase inhibitors are p38a MAP kinase inhibitors. The invention further provides compounds (I) for use in the methods for treatment of diseases comprising administration of MAP kinase inhibitors or compositions comprising MAP kinase inhibitors. In some embodiments, the disease is Alzheimer's Disease, ALS, Huntington's Disease or Parkinson's Disease.wherein X1 is CH and Xis N.