Karl Dane Wittrup,Jamie B. Spangler,Benjamin Joseph Hackel
申请号:
US13390086
公开号:
US20120270797A1
申请日:
2010.08.13
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention features engineered proteins that can include a genetically modified Fn domain two or more such domains joined to one another or at least one genetically modified Fn domain joined to a target-specific protein scaffold. One or more accessory sequences can be included in or added to any of these configurations. Methods of use, including methods of treating cancer, with the engineered proteins are also disclosed.