Sterile and liquid topical composition, useful to treat cosmetic imperfections of skin and/or lips, includes hyaluronic acid derivative with activated photodimerizable group that has double bond and stylbazolium and styrylazolium functions
Sterile and liquid topical composition comprises at least a hyaluronic acid derivative with an activated photodimerizable group that has at least a double bond and includes photodimerizable groups having stylbazolium function (I) or (II) and photodimerizable groups having styrylazolium function (III). Sterile and liquid topical composition comprises at least a hyaluronic acid derivative with an activated photodimerizable group that has at least a double bond and includes photodimerizable groups having stylbazolium function of formula (I) or (II) and photodimerizable groups having styrylazolium function of formula (III). R, R1a : H, 1-4C alkyl or 1-4C hydroxyalkyl； R1 : H or 1-4C alkyl； X ->；chlorine ion, bromine ion, iodine ion, perchlorate ion, tetrafluoroborate ion, methyl sulfate ion, phosphate ion, sulfate ion, methanesulfonate ion or p-toluenesulfonate ion； R2 : 2-8C divalent alkylene； and A : S, O, NR1 or C(R1) 2. Independent claims are included for: (1) cosmetic treatment of skin and/or the lips comprising topical administration of composition into or through the skin and/or lips, simultaneously illuminating the skin and/or lips to crosslink the composition； (2) a system for treatment of skin and/or the lips comprising a package containing at least a dose of the composition and a composition injection device； and (3) an assembly for treating cosmetic imperfections of skin and/or lips comprising a treatment system and an illumination system for photocrosslinking to the compound. [Image].La présente invention a pour objet une composition liquide et stérile et dédiée à une administration par voie topique ou dans ou à travers la peau et/ou les lèvres, ladite composition comprenant dans un milieu physiologiquement acceptable au moins un dérivé d'acide hyaluronique, caractérisée en ce que ledit dérivé comprend au moins un groupe photodimérisable activé possédant au moins une double liaison activée et choisi parmi les groupes photodimérisables portant une fonction
