David Hirst;Tianbao Chen;Martin O'Rourke;Christopher Shaw;Brian Walker
发明人:
Christopher Shaw,Tianbao Chen,Martin O'Rourke,Brian Walker,David Hirst,Martin ORourke
申请号：
US13530550
公开号：
US20120295851A1
申请日:
2012.06.22
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Described is an N-terminal hexapeptide fragment of maximakinin, QUB 698.8, which exhibits potent tissue selective actions on smooth muscle. It demonstrates a high degree of selectivity for arterial smooth muscle over small intestinal smooth muscle, causing potent relaxation of arterial smooth muscle, while causing less potent contraction of ileal smooth muscle. It may be used treatment of diseases of the cardiovascular system and in promotion of angiogenesis.
