etutle sensor • (74Aitie . :7te?' "i rxi t6 32 t q 200 FIG. 5 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 07 September 2018 (07.09.2018) WIP0 I PCT 0111111010 0111 °nolo omioollm offi VIII Imo oimIE (10) International Publication Number WO 2018/160135 Al (51) International Patent Classification: G01L 1/18 (2006.01) G01L 5/10 (2006.01) G01L 1/22 (2006.01) G01N 27/06 (2006.01) A61B 5/024 (2006.01) (21) International Application Number: PCT/SG2018/050076 (22) International Filing Date: 19 February 2018 (19.02.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/465,002 28 February 2017 (28.02.2017) US (71) Applicant: NATIONAL UNIVERSITY OF SINGA- PORE [SG/SG]； 21 Lower Kent Ridge Road, Singapore 119077 (SG). (72) Inventors: YEO, Joo Chuan； c/o National University of Singapore, Faculty of Engineering, Department of Biomed- ical Engineering, 21 Lower Kent Ridge Road, Singapore 119077 (SG). XI, Wang； c/o National University of Sin- gapore, Mechanobiology Institute, 21 Lower Kent Ridge Road, Singapore 119077 (SG). YU, Longteng； c/o Nation- al University of Singapore, Faculty of Engineering, Depart- ment of Biomedical Engineering, 21 Lower Kent Ridge Road, Singapore 119077 (SG). LIM, Chwee Teck； c/o Na- tional University of Singapore, Faculty of Engineering, De- partment of Biomedical Engineering, 21 Lower Kent Ridge Road, Singapore 119077 (SG). (74) Agent: AMICA LAW LLC； 30 Raffles Place, #14-01 Chevron House, Singapore 048622 (SG). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, L
