John Hynes;Percy H. Carter;Joseph B. Santella;Daniel S. Gardner;John V. Duncia;T.G. Murali Dhar
发明人:
Daniel S. Gardner,John V. Duncia,John Hynes,T.G. Murali Dhar,Percy H. Carter,Joseph B. Santella
申请号：
US12670016
公开号：
US08501782B2
申请日:
2008.07.23
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present application describes modulators of MIP-1α of formula (I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein m, Q, T, W, Z, R1, R3, R4, R5, R5a and R5b, are as defined herein. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis using the modulators of formula (I) are disclosed.
