James M. Tour,Jacob Berlin,Daniela Marcano,David S. Baskin,Martyn A. Sharpe
申请号：
US14114051
公开号：
US20140154269A1
申请日:
2012.04.26
申请国别(地区):
US
年份:
2014
代理人:
摘要：
In some embodiments, the invention pertains to therapeutic compositions for treating a brain tumor. Such therapeutic compositions generally comprise: (1) a nanovector (2) an active agent associated with the nanovector with activity against brain tumor cells and (3) a targeting agent associated with the nanovector with recognition activity for a marker of the brain tumor cells. In some embodiments, the active agent and the targeting agent are non-covalently associated with the nanovector. Additional embodiments of the present invention pertain to methods of treating a brain tumor in a subject (e.g., a human being) by administering the aforementioned therapeutic compositions to the subject. Further embodiments of the present disclosure pertain to methods of formulating therapeutic compositions for treating a brain tumor in a subject in a personalized manner.
