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Piperazindioner som oksytocinreseptorantagonister
专利权人:
Glaxo Group Limited
发明人:
Mason, Andrew McMurtrie,Liddle, John,Borthwick, Alan David,Hickey, Deidre Mary Bernadette
申请号:
NO20070173
公开号:
NO338769B1
申请日:
2007.01.10
申请国别(地区):
NO
年份:
2016
代理人:
摘要:
Compounds of formula (I) wherein R 1 is 2-indanyl, R 2 is 1-methylpropyl, R 3 is a group selected from 2, 6-dimethyl-3-pyridyl or 4,6-dimethyl-3-pyridyl, R 4 represents methyl and R 5 represents hydrogen or methyl or, R 4 and R 5 together with the nitrogen atom to which they are attached represent morpholino and pharmaceutically acceptable derivatives thereof are described, as are processes for their preparation, pharmaceutical compositions containing them and their use in medicine, particularly their use as oxytocin antagonists.
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