The present disclosure is in relation to the use of a composition comprising pentameric type A procyanidin, trimeric procyanidin and tetrameric procyanidin, optionally along with pharmaceutical excipient(s), in management of broncho-constrictive conditions such as Allergic Rhinitis, Asthma, and Chronic obstructive pulmonary disease (COPD).本發明係關於包含五聚A型原花青素(procyanidin)、三聚原花青素及四聚原花青素,視情況連同醫藥賦形劑之組成物之用途,其係用於控制支氣管收縮病狀,諸如過敏性鼻炎、哮喘及慢性阻塞性肺病(COPD)。