The present invention is included in the lipophilic molecules of the water-soluble form in liposome. In one embodiment, the lipophilic molecules are crystalline Luteins, and the liposome for loading lutein is included in drug products, medical device, in dietary supplements industry, and for chewable tablet, beverage reinforcings, effervescent tablet, without coated tablet, nutrition bar and functional food and cosmetics industry with potentiality.