PROBLEM TO BE SOLVED: To provide a syringe with an injection needle, even when sterilization by an autoclave or ethylene oxide gas is applied and stress that fastens the injection needle is generated, firmly joining the injection needle to an outer cylinder without causing decrease in joint strength between the injection needle and the outer cylinder.SOLUTION: A syringe 1 with an injection needle includes: an outer cylinder 2 molded with a resin, including a cylinder tip 21 at a distal end, an opening 25 at a proximal end, and a barrel part 23 having an inner cavity 22 filled with a drug solution 5, located therebetween； a joint portion 30 fixed to the cylinder tip 21； and an injection needle 3 projecting beyond the cylinder tip 21 at the distal end side, and allowing communication between the inside and outside of the outer cylinder 2, the injection needle 3 being fixed to the cylinder tip 21 by insert molding or heat welding. An uneven portion 32 having an average surface roughness of 0.2 μm or more is formed in a region having an area of 1 mmor more on an outer peripheral surface of the joint portion 30. The resin covers the uneven portion 32 in close contact therewith, so that sterilization by an autoclave or ethylene oxide gas is applied to the outer cylinder 2 having the injection needle 3 fixed thereto.SELECTED DRAWING: Figure 1【課題】オートクレーブ又はエチレンオキサイドガスによる滅菌処理が施されて、外筒に固定された注射針を締め付ける応力の緩和が生じても、注射針と外筒との接合強度の低下を生じさせず、注射針が外筒に確りと接合された注射針付シリンジを提供する。【解決手段】注射針付シリンジ１は、先端に筒先２１と、基端に開口２５と、その間に薬液５が充填される内空２２が設けられた胴部２３とを有し、樹脂で成形された外筒２と、筒先２１に固定された接合部３０と、筒先２１より先端側に突出し、外筒２の内外を連通させた注射針３とを備え、注射針３がインサート成形又は熱溶着により筒先２１に固定され、接合部３０の外周面上で面積１ｍｍ２以上の領域に平均表面粗さ０．２μｍ以上の凹凸部３２が設けられ、樹脂が凹凸部３２を密着して覆うことにより、注射針３が確実に固定された外筒２にオートクレーブ又はエチレンオキサイドガスによる滅菌処理が施されている。【選択図】図１
