To provide antibodies which recognize the extracellular domain of a human CLCP1 antigen, and to provide use thereof.SOLUTION: The present invention relates to an antibody recognizing a peptide consisting of particular amino acid sequences having the migration inhibitory activity, invasion inhibitory activity, growth inhibitory activity, metastasis inhibitory activity and cytotoxic activity of renal cancer, bladder tumor, prostate cancer, pancreatic cancer, gastric cancer, colon cancer, breast cancer or lung cancer cells expressing CLCP1； as well as a nucleic acid encoding the antibody； a vector expressibly retaining the nucleic acid； and a transformant having the vector.SELECTED DRAWING: None【課題】ヒトＣＬＣＰ１抗原の細胞外ドメインを認識する抗体及びその用途の提供。【解決手段】ＣＬＣＰ１を発現する、腎がん、膀胱腫瘍、前立腺がん、膵臓がん、胃がん、大腸がん、乳がん又は肺がん細胞の遊走阻害活性、浸潤阻害活性、増殖阻害活性、転移阻害活性、及び細胞障害活性を有する、特定のアミノ酸配列からなるペプチドを認識する抗体、及び該抗体をコードする核酸、該核酸を発現可能に保持するベクター、及び該ベクターを有する形質転換細胞。【選択図】なし
