Disclosed herein are methods and compounds for treating a motor-associated neurodegenerative disease or condition. In some instances, also included herein are methods and compounds for treating a TDP-43 associated neurodegenerative disease or condition (e.g., ALS and frontotemporal dementia) and/or a C9orf72 associated neurodegenerative disease or condition (e.g., ALS and frontotemporal dementia).
