Adjunct materials for delivery to stomach tissue are provided. In general, the adjunct materials can be configured to be delivered to tissue by deployment of staples from a cartridge body of a surgical stapler. The adjunct material can have a structure effective to cause a desired reaction in the stomach tissue. The adjunct material can include an effective amount of one or more medicants disposed within and releasable from the adjunct material for delivery to the stomach tissue to encourage the desired reaction. The adjunct material can be in the form of at least one of a film and a foam that is releasably retained on the cartridge body. Methods of using a staple cartridge assembly or an end effector to apply such adjunct materials to stomach tissue are also provided.
