DI PIETRO, TONY,HUMBERSTONE, ANDREW,GONDA, IGOR,WATKINSON, ADAM,SETIAWAN, KERRIE,WILKINS, NINA
申请号：
NZ56394606
公开号：
NZ563946A
申请日:
2006.06.02
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
Disclosed is the use of a non-occlusive transdermal drug delivery composition in the manufacture of a medicament for application to at least one axilla (arm pit) of a person, without occlusion by a patch device, for the treatment of testosterone deficiency, the composition comprising: (a) a pharmaceutically effective amount of at least one androgen selected from testosterone and pharmaceutically acceptable salts thereof； (b) a solvent selected from the group consisting of ethanol, isopropanol and mixtures thereof in an amount of at least 60% v/v of the composition； (c) one or more penetration enhancers selected from the group consisting of glycols, oleic acid, isopropyl myristate, cyclopentadecanone, sorbitan monooleate, octyl salicylate, octyl dimethyl-para-aminobenzoate and octyl paramethoxycinnamate； (d) one or more viscosity modulating agents； e) optionally, an activator for the viscosity modulating agent； (f) optionally, an antiperspirant and/or deodorant agent； and (g) optionally, water.
