1. A composition for the treatment and / or prevention of angiogenesis-related eye disease, comprising a low dose rodostomina variant comprising an amino acid sequence selected from SEQ ID NO: 1 - SEQ ID NO: 16, or a pharmaceutically acceptable salt of said rodostomina.2 embodiment. A composition according to claim 1, wherein said amino acid sequence selected from SEQ ID NO: 9 and SEQ ID NO: 15.3. A composition according to claim 1, wherein said amino acid sequence is SEQ ID NO: 15.4. A composition according to claim 1, wherein said variant is conjugated to albumin rodostomina or pegilirovan.5. The composition of claim 1 wherein the low dose is from about 0.0001 pg to about 300 micrograms of said rodostomina.6 embodiment. The composition of claim 1 wherein the low dose is from about 0.0005 pg to about 200 micrograms of said rodostomina.7 embodiment. The composition of claim 1 wherein the low dose is from about 0.001 pg to about 100 micrograms of said rodostomina.8 embodiment. A composition according to claim 1, wherein said composition is formulated as a composition for topical primeneniya.9. A composition according to claim 1, wherein said composition is formulated as an injectable kompozitsiya.10. A composition for the treatment and / or prevention of angiogenesis-related eye disease, comprising a low dose rodostomina variant comprising the amino acid sequence of SEQ ID NO: 15, or a pharmaceutically acceptable salt of said rodostomina.11 embodiment. The method of treatment and / or prevention of angiogenesis-related eye disease, comprising administering to a subject in need thereof, by p.1.12 composition. The method of treatment and / or prophylaxis of connectedness1. Композиция для лечения и/или профилактики связанного с ангиогенезом заболевания глаз, содержащая низкую дозу варианта родостомина, содержащего аминокислотную последовательность, выбранную из SEQ ID NO: 1 - SEQ ID NO: 16, или фармацевтически приемлемой соли упомянутого варианта родостомина.2. Композиц