4-[5-(吡啶-4-基)-1H-1,2,4-三唑-3-基]吡啶-2-碳腈之結晶多形及其製造方法农业专利-农业学术服务平台

发明人:: IWABUCHI, YOSHIYUKI,岩渊刚行,岩淵剛行,MIYATA, SACHIHO,宫田幸帆,宮田幸帆,SATO, TAKAHIRO,佐藤隆弘,UDA, JUNICHIRO,雨田淳一郎,KANDOU, TAKAMITSU,神藤高光,INOUE, TADASHI,井上正,NAKANO, HIROYUKI,中野浩行

摘要：: To provide crystal polymorphs of 4-[5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile, which is a useful pharmaceutical, and a production method therefor. Through purification of a corresponding salt, recrystallization, or storage under humidified conditions, three different crystal forms； i.e., crystalline polymorphs of 4-[5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile are produced.本發明提供一種用作醫藥品之4-[5-(吡啶-4-基)-1H-1,2,4-三唑-3-基]吡啶-2-碳腈之結晶多形及製造方法。本發明係關於一種4-[5-(吡啶-4-基)-1H-1,2,4-三唑-3-基]吡啶-2-碳腈之結晶多形，藉由經由鹽之純化、再結晶或加濕條件下之保存，獲得不同之3種結晶形。