A device to deliver and maintain reduced pressure to body surfaces for application of reduced pressure wound therapy (RPWT) also known as negative pressure wound therapy (NPWT). A substantially airtight seal is formed around a section of tissue to be treated. This seal is formed by a dressing which provides fluid communication from a section of tissue to a reduced pressure source. The system may be configured to allow full rotation of the fluid communication conduit to the reduced pressure source. The system may be configured to include a one-way valve to prevent backflow of any drainage fluids, and with transparent windows covered by opaque flaps to allow inspection through the dressing. The system may be configured to include an indicator which visually makes clear whether reduced pressure is being applied or not. Also, the system is configured to minimize the profile of the dressing system.