The invention discloses a fastener cartridge comprising deployable tissue engaging members. The fastener cartridge (2000) can comprise fastener cavities (2050) arranged in longitudinal rows. A first fastener (2130) having a first configuration and a second fastener (2130) having a second configuration can be stored within a longitudinal row. First fasteners having a first configuration can be stored within a first longitudinal row and second fasteners having a second configuration can be stored within a second longitudinal row. Each first fastener can have a proximal leg (2132a), or leg portion, extending at a first proximal angle (F) and a distal leg (2132b), or leg portion, extending at a first distal angle (G) and each second fastener can have a proximal leg, or leg portion, extending at a second proximal angle and a distal leg, or leg portion, extending at a second distal angle. The first proximal angle can be different than the second proximal angle and/or the first distal angle can be different than the second distal angle.
