A staple pocket arrangement on the anvil portion of a surgical stapler device includes pairs of staple pockets corresponding to each one of a plurality of staples to be closed. Each respective staple leg is received at a longitudinal end of the staple pocket that provides a relatively wide target area for receiving the staple leg to eliminate or at least minimize the likelihood that a staple leg will miss the staple pocket. The staple pockets may be arranged in rows, each row of staple pockets being longitudinally offset from another row, such that each staple pocket in a first row of staple pockets is nested with a staple pocket from an adjacent row of staple pockets to make more efficient use of space on the anvil.
