This invention provides a vesicle composition, and a dermatological agent for topical use and a cosmetic material comprising thereof.The vesicle composition comprises a vesicle, which has a constituting membrane comprising ingredients (A) and (B) as following.(A)etheric non-ionic surfactant having a sterol backbone (B)mono-alkyl glyceryl ether.The dermatological agent for topical use and the cosmetic material individually comprises a vesicle composition, which comprises a vesicle having a constituting membrane comprising ingredients (A) and (B) as following.(A)etheric non-ionic surfactant having a sterol backbone (B)mono-alkyl glyceryl ether.本發明提供經時安定性優異之囊泡組成物、含它之皮膚外用劑及化妝品材料。[1]該囊泡組成物含有具有構成膜之囊泡,該構成膜包含以下成分(A)及(B):(A)作為具有固醇骨架之醚系非離子性界面活性劑的聚氧伸烷基固醇醚;(B)單烷基甘油基醚,前述成分(A)聚氧伸烷基固醇基醚的含量為0.01~10質量%,及前述成分(B)單烷基甘油基醚的含量為0.01~5質量%。[2]該皮膚外用劑及化妝品材料包含囊泡組成物,該囊泡組成物含有具有構成膜之囊泡,該構成膜包含以下成分(A)及(B):(A)具有固醇骨架之醚系非離子性界面活性劑;(B)單烷基甘油基醚。圖式中並無適合作為代表圖者。
