PROBLEM TO BE SOLVED: To provide a hemostatic agent that can firmly coagulate blood without the use of a blood-derived material.SOLUTION: Provided is a polysaccharide hemostatic agent that is made from a polysaccharide such as hyaluronic acid composed of a plurality of constituent units as a raw material and in which an aldehyde group and a hydrophobic group are introduced into at least a part of the constituent units. The protein in the blood is coagulated by the aldehyde group introduced into the polysaccharide, as well as the blood cell is coagulated by the hydrophobic group also introduced.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】血液由来材料を使用せずに、血液を強固に凝固させることができる止血剤を提供する。 【解決手段】複数個の構成ユニットからなるヒアルロン酸等の多糖を原料とし、その構成ユニットの少なくとも一部にアルデヒド基及び疎水基を導入した多糖止血剤。多糖に導入されたアルデヒド基により血中のたんぱく質を凝固させるとともに、同じく導入された疎水基により血球を凝固させる。【選択図】なし