NOUVELLE MOLECULE ASSOCIEE A UNE TUMEUR HUMAINE METASTATIQUE, PROCEDES POUR DETECTER A LA FOIS UNE PROTEINE ET UN GENE ACTIVES ET POUR INTERFERER AVEC L'EXPRESSION DU GENE
This disclosure characterizes the function and the expression of the humanprotein encoded by tm9sf4. The proteinis highly expressed in malignant tumor cells and therefore is a novel markerfor malignancy. Moreover, the protein is involved in thephagocytotic character of tumor cells. This disclosure provides methods andtools to diagnose and follow up malignancy of tumors.Furthermore, means to inhibit phagocytotic character of tumor cells as well asmeans to treat cancer are provided.