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Alkynyl pyrrolo[2,3-d]pyrimidines and related analogs as HSP90-inhibitors
专利权人:
Marco Antonio Biamonte;Jiandong Shi;Srinivas Rao Kasibhatla;Marcus F. Boehm
发明人:
Srinivas Rao Kasibhatla,Marco Antonio Biamonte,Jiandong Shi,Marcus F. Boehm
申请号:
US12471298
公开号:
US08093229B2
申请日:
2009.05.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Alkynyl pyrrolo [2,3-d] pyrimidines of Formula I are described and demonstrated to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents used in the treatment and prevention of various HSP90 mediated disorders. Methods of synthesis and use of such compounds are also described and claimed.
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