Chucholowski, Alexander,Shum, David,Somwar, Romel,Varmus, Harold E.,Thiruvazhi, Mohan Santhanam,Djaballah, Hakim
申请号:
AU2014233641
公开号:
AU2014233641A1
申请日:
2014.09.26
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
#$%^&*AU2014233641A120141016.pdf#####H:\sxd\lnterwoven\NRPortbl\DCC\SXD\68307431.docx-26/09/2014 ABSTRACT The present invention is directed to pyridazinone compounds of formula (I) and furan compounds of formula (II), pharmaceutical compositions of compounds of formula (I) and (II), kits containing these compounds, methods of syntheses, and a method of treatment of a proliferative disease in a subject by administration of a therapeutically effective amount of a compound of formulae (I) or (II). Both classes of compounds were identified through screening of a collection of small molecule libraries.