THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;PAGANINI BIOPHARMA, INC.
发明人:
WADEHRA, MADHURI,BRAUN, JONATHAN,GORDON, LYNN K.,LAZAR, GARY S.
申请号：
CA2868791
公开号：
CA2868791A1
申请日:
2013.03.14
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Reduction of EMP2 expression and/or anti-EMP2 therapy reduces cancer stem cells in multiple types of cancer. For example, breast cancers stem cells were defined by the presence of HIF-1a, CD44 and ALDH. It is found that anti-EMP2 IgG1 can be used to reduce the numbers of cancer stem cells.
