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INFLUENZA VACCINES
专利权人:
ГАММА ВАКСИНС ПТИ ЛИМИТЕД (AU)
发明人:
АЛШАРИФИ Мохаммед (AU),МУЛЛБАХЕР Арно (AU)
申请号:
RU2011107757/15
公开号:
RU2011107757A
申请日:
2009.07.31
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. A method for treating or preventing infection with multiple subtypes of influenza virus in a subject, the method comprising administering to the subject intranasally a therapeutically effective amount of a gamma-irradiated influenza virus. ! 2. The method according to claim 1, where the specified gamma-irradiated influenza virus is obtained from the source of viral material purified by tangential filtration / filtration in a cross stream. ! 3. The method according to claim 1, where the specified gamma-irradiated influenza virus is created using gamma radiation of a frozen viral preparation. ! 4. The method according to claim 1, where the specified gamma-irradiated influenza virus is obtained in lyophilized form. ! 5. The method according to claim 1, where these multiple subtypes of influenza virus include one or more of the subtypes of human, avian, swine, canine or equine influenza virus. ! 6. The method according to claim 1, where these multiple subtypes of influenza virus include a subtype of HPAI A (H5N1) influenza A or swine flu subtype of H1N1 09 influenza A.! 7. The method according to claim 1, where the specified gamma-irradiated influenza virus is selected from the group consisting of A / WSN [H1N1], A / PR8 [H1N1], A / JAP [H2N2] and A / PC [H3 / N2] . ! 8. The method according to claim 1, where the specified gamma-irradiated influenza virus is created by exposing the specified virus to a total dose of from about 6.5 · 104 rad to about 2 · 107 rad gamma rays. ! 9. A method of inducing or enhancing cross-reactive immunity against multiple subtypes of influenza virus in a subject, the method comprising administering to the subject intranasally a therapeutically effective amount of gamma-irradiated influenza virus. ! 10. The method according to claim 9, where the specified cross-reactive immunity includes cross-reactive cellular immunity1. Способ лечения или профилактики инфицирования множественными подтипами вируса гриппа у субъекта, при этом способ включ
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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