WHELAN, MICHAEL ANTHONY,RAMIREZ CEBALLOS, ALEJANDRO,CRESCENTE, VINCENZO
申请号:
CA2969492
公开号:
CA2969492A1
申请日:
2015.12.03
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The invention provides a protein comprising hepatitis B core antigen (HBcAg) and influenza virus A surface polypeptide M2 or an immunogenic fragment thereof. The invention also provides a protein comprising hepatitis B core antigen (HBcAg) and influenza virus hemagglutinin (HA) or an immunogenic fragment thereof. The invention also provides particles formed from the proteins, nucleic acid molecules encoding the proteins, processes for producing the proteins, pharmaceutical compositions containing the proteins and use of the proteins to induce an immune response in a subject.