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Heteroarylpiperidine and heteroarylpiperazine derivatives
专利权人:
Bayer Intellectual Property GmbH
发明人:
Tsuchiya, Tomoki,Wasnaire, Pierre,Hoffmann, Sebastian,Seitz, Thomas,Hillebrand, Stefan,Benting, Jürgen,Schmidt, Jan Peter
申请号:
ES15154126
公开号:
ES2647443T3
申请日:
2012.12.21
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
Compounds of formula (Xa), ** Formula ** in which the definitions of moieties have the following meanings: RB1 represents hydrogen, cyano, hydroxy, C1-C3 alkyl, C2-C3 alkenyl, C2-C3 alkynyl, C1- haloalkyl C3, C2-C3 haloalkenyl, C2-C3 haloalkynyl, C2-C3 alkylcarbonyl, C2-C3 haloalkylcarbonyl, C1-C3 alkoxy, C1-C3 haloalkoxy, C1-C3 alkylthio, C1-C3 haloalkylthio, C1-C2 alkylcarbonyloxy, C1-C2alkylcarbonyl C2, RB2 represents hydrogen, X represents carbon, R2 represents hydrogen, p represents 0, G represents ** Formula ** RG1 represents hydrogen, Q represents ** Formula ** R5 represents hydrogen, L2 represents a direct bond, R1 represents phenyl that it is substituted at least once with a substituent Z4 and otherwise it can be substituted or unsubstituted, where the substituents independently from each other are selected from Z4 and in the case of Z1-2, or Z1-2 represents hydrogen, halogen, cyano , hydroxy, amino, nitro, C1-C6 alkyl, alkenyl C2-C6, C2-C6 alkynyl, C1-C6 haloalkyl, C2-C6 haloalkenyl, C2-C6 haloalkenyl, C3-C8 cycloalkyl, C3-C8 halocycloalkyl, C3-C8 cycloalkenyl, C3-C6 halocycloalkenyl, C-C6-C1-C6 alkoxy C1-C6 alkyl, C1-C6 alkylcarbonyl, C3-C8 cycloalkylcarbonyl, C1-C6 alkoxycarbonyl, C1-C6 alkoxy, C1-C6 haloalkoxy, C3-C8 cycloalkoxy, C1-C6 alkylcarbonyloxy, C1-C6 alkylcarbonyl, C1-C6 haloalkylthio, C3-C6 cycloalkylthio, C1-C6 alkylsulfonyl, C1-C6 haloalkylsulfonyl, C3-C8 cycloalkylsulfonyl, tri (C1-C4-alkyl) silyl or -L3Z3, L3 represents a direct bond, -CH2-, sulfur, oxygen or - (S>; = O) 2- Z3 represents a phenyl, naphthalenyl or a 5- or 6-membered heteroaryl moiety, which may contain up to two substituents, where the substituents independently from each other are selected from the following list: halogen, cyano, nitro, hydroxy, amino, -SH, C1-C4 alkyl, C2-C4 alkenyl, C2-C4 alkynyl, C1-C4 haloalkyl, C2-C4 haloalkenyl, C2-C4 haloalkynyl, alkoxy C2-C4 alkyl, C1-C6 alkylcarbonyl, C1-C6 haloalkylcarbonyl, C1-C6 alkoxycarbonyl, C1-C4 alkoxy, C1-C4 haloalkoxy,
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