INDAZOLE DERIVATIVES农业专利-农业学术服务平台

发明人:: CHERUVALLATH, ZACHARIA,契若维拉札奇瑞亚,契若維拉札奇瑞亞,ERICKSON, PHILIP,艾克森飞利浦,艾克森飛利浦,FENG, JUN,冯军,馮軍,KOMANDLA, MALLAREDDY,柯曼德拉曼勒地,柯曼德拉曼勒地,LAWSON, JOHN DAVID,罗森约翰大卫,羅森約翰大衛,MCBRIDE, CHRISTOPHER,麦克布莱德克里司多福

摘要：: Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, and R6 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating obesity and related diseases, disorders, and conditions associated with MetAP2.本文揭露式1化合物,及其醫藥學上可接受之鹽,其中R1、R2、R3、R4、R5及R6係在說明書中定義。本揭露內容亦係關於用於製備式1化合物之材料及方法;含有該等式1化合物之醫藥組合物;以及其用於治療肥胖症及與MetAP2相關之有關疾病、病症及病狀之用途。