An objective of the present invention is to provide a pharmaceutical composition for treatment of infertility.The present invention is related to a pharmaceutical composition used to be injected into intrauterine cavity, wherein the pharmaceutical composition includes adipose derived reproduction cells that contain an adipose derived stem cell, a vascular endothelial cell, and s vascular pericyte. The present invention is also related to a method for producing a pharmaceutical composition for treatment of infertility, wherein the method comprises obtaining a de-agglutinated tissue by treating an adipose tissue with a de-agglutinant, concentrating a reproduction cells by centrifuge treatment of the de-agglutinated tissue, and recovering the concentrated the reproduction cells.本發明之課題係提供一種可改善不孕症之醫藥組成物及其製造方法。本發明係關於一種子宮內腔投予用之醫藥組成物，係含有源自脂肪組織之再生細胞，該源自脂肪組織之再生細胞含有脂肪幹細胞、血管內皮細胞及血管外皮細胞。並且本發明關於一種不孕症之處置所用的醫藥組成物之製造方法，係包括將脂肪組織以去凝集劑處理而得到去凝集組織、從去凝集組織藉由離心處理而濃縮再生細胞、以及將經濃縮之再生細胞回收。
