Patrick C.H. Hsieh;Christopher Yu-Tai Yen;Academia Sinicia;David Lundy
发明人:
Patrick C.H. Hsieh,David Lundy,Christopher Yu-Tai Yen
申请号：
US16477558
公开号：
US20200121799A1
申请日:
2018.01.12
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A drug delivery system and methods of using such for delivering a peglyated therapeutic agent to brain. The drug delivery system may comprise an antibody, which binds polyethylene glycol (PEG), wherein the antibody is embedded in a hydrogel, which may comprises one or more biodegradable polymers, up to 60% of which contain inter-chain or intra-chain covalent crosslinks. The amount of the antibody in the drug delivery system can be about 1-2 μg per μl of the hydrogel.
