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Stent coating for eluting medication
专利权人:
Robert C. OBrien
发明人:
Robert C. OBrien,Christine A. Frysz
申请号:
US12755777
公开号:
US08367151B2
申请日:
2010.04.07
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assembly in a sputter flux. The result is a coating that is evenly distributed over the outward-facing side of the stents wire mesh while preventing the sputtered columnar coating from reaching the inward facing side where a smooth hemocompatible surface is required. The stent is then removed from the mandrel, exposing all surfaces, and finally coated with a layer of carbon such as amorphous carbon or diamond-like carbon. The carbonaceous coating enhances biocompatibility without preventing elutriation of a therapeutic drug provided in the porosity formed between the columnar structures. The result is a stent that is adapted to both the hemodynamic and the immune response requirements of its vascular environment.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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