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Fusion protein comprising albumin and retinol-binding protein
专利权人:
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
发明人:
Jun Seo Oh
申请号:
US15615099
公开号:
US10064915B2
申请日:
2017.06.06
申请国别(地区):
US
年份:
2018
代理人:
摘要:
There is provided a fusion protein comprising albumin and retinol-binding protein (RBP), which can be used for preventing or treating fibrotic diseases. The fusion protein, in which albumin and RBP are bound together, is incorporated into stellate cells and induces phenotypic reversion from myofibroblast-like cells to quiescent fat-storing phenotype. Therefore, the fusion protein can be effectively used in preventing or treating fibrotic diseases occurring in the liver, pancreas, lung, or other organs.
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