Scalable synthesis of reduced toxicity derivative of amphotericin B

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专利权人:

The Board of Trustees of The University of Illinois

发明人:

Burke, Martin D.,Uno, Brice E.,Rakshit, Souvik

申请号：

AU2015331904

公开号：

AU2015331904A1

申请日:

2015.10.16

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

Disclosed is a simplified, readily scalable series of individual methods that collectively constitute a method for the synthesis of C2'epiAmB, an efficacious and reduced-toxicity derivative of amphotericin B (AmB), beginning from AmB. Also provided are various compounds corresponding to intermediates in accordance with the series of methods.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/