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Methods of Making Implantable Collagen Devices
专利权人:
MiMedx Group; Inc.
发明人:
Thomas J. Koob
申请号:
US14618310
公开号:
US20150152381A1
申请日:
2015.02.10
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention relates to implantable collagen devices made by seeding at least one elongate collagen construct, e.g., comprising at least one elongate synthetic collagen fiber with a plurality of cells and applying a strain and/or stress to the at least one elongate collagen fiber to induce the cells to differentiate into target phenotypes, e.g., tendon or ligament phenotype cells (and/or fibroblasts), typically with an extracellular matrix of collagen to organize into a tissue on the at least one collagen fiber.
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