Evangelos V. Badiavas,Arsalan Q. Shabbir,Stephen C. Davis
申请号：
US14775382
公开号：
US10500231B2
申请日:
2014.03.12
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to the fields of medicine, cell biology, molecular biology and genetics. In particular, the present invention provides methods to isolate and purify microvesicles from cell culture supernatants and biological fluids. The present invention also provides pharmaceutical compositions of microvesicles to promote or enhance wound healing, stimulate tissue regeneration, remodel scarred tissue, modulate immune reactions, alter neoplastic cell growth and/or mobility, or alter normal cell growth and/or mobility. The present invention also provides compositions of microvesicles to be used as diagnostic reagents, and methods to prepare the compositions of microvesicles.
