A catheter securement device adapted to be adhesively mounted to the skin of a patient to secure a catheter in place, the device having a flexible, thin, sheet-like base member with a distal edge and a midportion, and a releasable, flexible, thin, sheet-like retention member. The retention member may include a first releasable end, a second releasable end, a proximal edge, and a distal edge. The distal edge of the retention member is offset from the distal edge of the base member to define an uplift focus area in the midportion of the base member, such that upward pull on the catheter is transferred to the midportion of the base member to preclude the base member from being peeled from the patient's skin. The retention member may be releasably attached to the base member using a hook-and-loop fastener impregnated with adhesive.
