An antiseptic, polymer-lipid or emulsification agents-based aqueous composition can be used for intraoral removal of denture adhesive residuals. More particularly, the present invention relates to employing a polymer-lipid based or a mixture of polymer-lipids and emulsification agents or a mixture of emulsification agents and Co-emulsification agents for convenient and effective removing the denture adhesive residuals intra mouth or a combination of two ore more polymer-lipids or emulsification agents or Co-emulsification agents thereof.