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diaryl macrocycle polymorph
专利权人:
INC.;TP THERAPEUTICS
发明人:
EVAN W. ROGERS,JINGRONG J. CUI,EVAN W ROGERS,JINGRONG J CUI
申请号:
BR112018000297
公开号:
BR112018000297A2
申请日:
2016.07.05
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
This disclosure relates to polymorphs of (7S,13R)-11-fluoro-7,13-dimethyl-6,7,13,14-tetrahydro-1,15-ethenopyrazolo[4,3-f][1,4,8,10]benzoxatriazacyclotridecin-4(5H)-one that are useful in the treatment of disease, such as cancer, in mammals. This disclosure also relates to compositions including such polymorphs, and to methods of using such compositions in the treatment of diseases, such as cancer, in mammals, especially in humans.
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