There is disclosed a method of treating a disease associated with increased levels of chemokine CXCLl7 is provided. The method includes administering to a subject in need of such treatment a therapeutically effective amount of a substance that lowers the level of CXCLl7 activity. The substance that lowers the level ofCXCLl7 activity can be an antiCXCLl7 antibody, which can be a monoclonal antibody. In other embodiments, the substance can be an antisense compound targeting CXCLl7, which can be an antisense oligonucleotide or an siRNA. In another aspect, a method of treating a tumor in a subject in need of such treatment is provided as well as a method of diagnosing a disease associated with increased levels of chemokine CXCL17.Un método para tratar una enfermedad asociada con mayores niveles de la quimiocina CXCL17 el método incluye administrarle a un sujeto que necesite dicho tratamiento una cantidad terapéuticamente eficaz de una sustancia que reduzca el nivel de actividad de CXCL17 la sustancia puede ser un anticuerpo de CXCL17 o un compuesto antisentido dirigido a CXCL17 como un oligonucleótido antisentido o un ARNip también se proporcionan métodos para tratar tumores con CXCL17 y métodos para diagnosticar una enfermedad asociada con mayores niveles de CXCL17.
