WARCHOL, MARK P.,MOREN, FOLKE,THYRESSON, KRISTINA,STHENGEL, ELISABETH,ANDERSSON, SVEN-BOERJE
申请号:
CA2487699
公开号:
CA2487699C
申请日:
2003.05.30
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The composition consists of liquid pharmaceutical formulation comprisingnicotine in any form for administration essentially to the lungs. Theformulation is acidified and/or alkalized by buffering and/or pH regulation,which provides a tmax of nicotine in arterial blood of a subject within ashort period of time after administration. The administration preferablyimplies spraying an aerosol into the oral cavity for further distribution,essentially to the lungs. A method for manufacturing the formulation is alsoincluded, as well as use of the formulation in therapy, e.g. for treatingaddiction to tobacco.