Shankar Kumar;J. Yun Tso;Naoya Tsurushita;Nicholas F. Landolfi
发明人:
J. Yun Tso,Naoya Tsurushita,Nicholas F. Landolfi,Shankar Kumar
申请号：
US13082352
公开号：
US09028830B2
申请日:
2011.04.07
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention provides monoclonal antibodies that specifically bind to CD122, which is one component of receptors for IL-2 and IL-15. The monoclonal antibodies have the capacity for substantial inhibition of both IL-2 and IL-15 mediated functions by inhibiting binding of these cytokines to their receptors. The monoclonal antibodies can be used for inhibiting undesired immune responses or treatment of cancer, among other applications.
