Marc Blouin,Jason Burch,Yongxin Han,Christophe Mellon
申请号:
US12309941
公开号:
US08969394B2
申请日:
2007.08.10
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention is directed to thiophenecarboxamide derivatives of formulae I and II as EP4 receptor ligands, antagonists or agonists, useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis, cancer and glaucoma. Pharmaceutical compositions and methods of use are also included. (Formulas I and II).