A pill box is provided, including a main body, having an elongated hole, the elongated hole including an inlet end portion and an outlet end portion which are open toward two different sides of the main body, the main body further including a pill guiding portion which protrudes outwardly and a cap portion, the pill guiding portion having a guiding opening, the cap portion openably covering the guiding opening; a plurality of case bodies, each of the plurality of case bodies movably engaged and positionable in the elongated hole, each of the plurality of case bodies including an opening communicable with the guiding opening when located close to the guiding opening.